Adenosine-induced pulmonary vein ectopy as a predictor of recurrent atrial fibrillation after pulmonary vein isolation.

Differential effects of adenosine on pulmonary vein ectopy after pulmonary vein isolation: implications for arrhythmogenesis.

BACKGROUND The mechanism of pulmonary vein (PV) triggers of atrial fibrillation remains unclear. We performed adenosine (ADO) testing after PV isolation to characterize spontaneous dissociated PV rhythm and ADO-induced PV ectopy. METHODS AND RESULTS Seventy-four patients (61 men; age, 61±10 years) undergoing PV isolation for atrial fibrillation were studied. For each isolated PV, dissociated ...

Clinical implication of adenosine test at repeat atrial fibrillation ablation procedure: the importance of detecting dormant thoracic vein conduction.

BACKGROUND Pulmonary vein reconnection after electrical isolation is commonly observed in the context of atrial fibrillation ablation and is associated with recurrent atrial tachyarrhythmias. Adenosine test was been performed to identify acute dormant conduction immediately after pulmonary vein isolation at index procedure. However, the utility of adenosine test at repeat procedure has not been...

Repeated Provocation of Time- & ATP-induced Early Pulmonary Vein Reconnections after Pulmonary Vein Isolation: Eliminating Paroxysmal Atrial Fibrillation in a Single Procedure

Sustained Dissociated Irregular Tachycardia in Two Pulmonary Veins After Radiofrequency Ablation of Atrial Fibrillation

A 64-year-old woman underwent radiofrequency ablation of atrial fibrillation. After pulmonary vein (PV) isolation, she converted into sinus rhythm. However, irregular PV tachycardia “trapped” in the right and left superior pulmonary vein (RSPV/LSPV) sustained. Fifteen minutes after RSPV isolation, the RSPV tachycardia terminated. However, sustained LSPV tachycardia was still present after one h...

Adenosine-induced atrial fibrillation: insights into mechanism.

A trial fibrillation (AF) is a potential adverse effect of intravenous administration of adenosine. Although the mechanism is not known, this phenomenon is thought to be mediated by adenosine's effects on shortening atrial action potential duration and refractoriness. Because ade-nosine has little effect on atrial conduction velocity, the net effect of adenosine, therefore, is to shorten the wa...